Assuredly, that to which you invite me has no [response to a] supplication in this world or in the Hereafter; and indeed, our return is to Allah , and indeed, the transgressors will be companions of the Fire.
Meaning:-
Supplication: the action of asking or begging for something earnestly or humbly.
Transgressors: to violate a law, command, moral code, etc.; offend; sin.